| Simultaneous Evaluation of Magnesia and Silica
Contents’ Effect on in-vitro Bioactivity of Novel
Bioglasses in the SiO2-CaO-MgO System |
Masoud Eslami,a, * Zahra Mahdieh,a Vahid Maddahi,a Mohammad Ali Shokrgozarb and
Morteza Mehrjoob
pages : 7-11
DOI: 10.1080/0371750X.2015.1131628 |
| Abstract |
| In this study, bioglasses in SiO2-CaO-MgO system were synthesized through sol-gel
method and the effect of silica and magnesia contents on in-vitro bioactivity of the
bioglasses were investigated. XRD patterns showed an amorphous structure after
heat treatment at 600oC for 2 h for all glasses and also indicated that after immersion
in SBF, apatite particles precipitated on glass surfaces and the rate of apatite formation
decreased with increasing Mg/Ca ratio. On the other hand, the apatite formation rate
was enhanced with increasing the silica content. Furthermore, magnesia contents
increased the compressive strength of the samples. According to SEM, higher Mg/Ca
ratio led to increase in particle size of the precipitated apatite. MTT assay showed that
cell proliferation was inhibited with increasing Mg/Ca ratio, however, silica contents
stimulated the osteoblast proliferation.
[Keywords: Bioglass, Silica, Bioactivity, Magnesia] |
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